What does an XYY person look like?

Boys with XYY syndrome may have some or all of these physical symptoms to some degree: taller than average height. low muscle tone, or muscle weakness (called hypotonia) very curved pinky finger (called clinodactyly)

What happens when someone is XYY?

The extra X and/or Y chromosome can affect physical, developmental, behavioral, and cognitive functioning. Common physical features may include tall stature, lack of secondary pubertal development, small testes (hypogonadism), delayed pubertal development, and breast development (gynecomastia) in late puberty.

Is XYY a disability?

47,XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Affected children can have delayed development of motor skills (such as sitting and walking) or weak muscle tone (hypotonia).

What is an XYY female?

Instead of having one X and one Y sex chromosome, those with XYY syndrome have one X and two Y chromosomes. Sex chromosome abnormalities like XYY syndrome are some of the most common chromosome abnormalities. (

What part of the body does XYY syndrome affect?

For some males with this syndrome, signs and symptoms are barely noticeable. For others, signs and symptoms may include learning disabilities, speech delay, low muscle tone (hypotonia), and being taller than expected. 47, XYY syndrome is caused by having an extra copy of the Y chromosome in every cell of the body.

The myth of the "supermale" and the extra Y chromosome

Is XYY syndrome autism?

XYY syndrome is a sex chromosome aneuploidy that occurs in ~ 1/850 male births and is associated with increased risk for neurodevelopmental difficulties. However, the profile of neurodevelopmental impairments, including symptoms of autism spectrum disorder (ASD) in XYY remains poorly understood.

What event is most likely to cause XYY syndrome?

It most commonly arises during meiosis II in the father, at which time an extra Y chromosome is attributed to the resultant sperm. [2] An alternate and less common form of this condition is 46,XY/47,XYY mosaicism, which arises during early embryonic development.

Can XYY get pregnant?

Men with 47, XYY syndrome that show normal semen parameters can achieve pregnancy spontaneously. However, for infertile men who have difficulty achieving pregnancy, IVF or ICSI may be required.

Which parent causes XYY syndrome?

XYY syndrome is not caused by anything the parents did or did not do. The disorder is a random error in cell division. This error can happen before conception in the reproductive cells of the mother or the father, or early in the embryo's development.

Is XXY a mother or father?

Klinefelter syndrome is not directly inherited – the additional X chromosome occurs as a result of either the mother's egg or the father's sperm having the extra X chromosome (an equal chance of this happening in either), so after conception the chromosome pattern is XXY rather than XY.

How long do people with XYY syndrome live?

The median age of survival was 77.9 years for controls and 67.5 years for 47,XYY persons, corresponding to a loss of median lifespan of 10.3 years. Kaplan-Meier survival graphs in 47,XYY compared to an age-matched male background population.

Can XYY be a girl?

47,XYY is a chromosomal abnormality syndrome that is typically observed in patients with a male phenotype. Few patients with XYY syndrome will have infertility. We here report a case of 46,XY/47,XYY syndrome diagnosed in a patient with a female phenotype.

Is XYY syndrome intersex?

XYY would seem to fit the current DSD classification definition of 'congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical' (Hughes et al., 2006: 554); however, XYY is not considered to be an intersex variation or a DSD.

Can XYY syndrome be cured?

The XYY syndrome cannot be cured. But treating the symptoms caused by this genetic disorder is possible. The syndrome is caused due to the cell division error in the sperm cells before or after conception. Men with this condition have an extra copy Y chromosome in all or some cells of their body.

Do serial killers have an extra Y chromosome?

STUDIES SOON BEGAN TO APPEAR, AND IT WAS LATER DISCOVERED THAT SOME OF SOCIETY'S MOST NOTORIOUS MURDERERS (E.G., ROBERT PETER TAIT, DANIEL HUGON, JOHN FARLEY) HAD THE EXTRA Y CHROMOSOME.

CAN XXY have babies?

It is possible that an XXY male could get a woman pregnant naturally. Although sperm are found in more than 50% of men with KS³, low sperm production could make conception very difficult.

What is the difference between XYY and XXY?

Despite having fewer learning and language problems than the 47,XXY group, males with 47,XYY have been reported to be more disruptive and impulsive, which greatly interferes with their learning skills. Males with 47,XXY are typically shy and withdrawn compared to 47,XYY.

Why is Klinefelter so tall?

From early school age, boys with Klinefelter syndrome tend to be taller (increased leg length) in part because testosterone (via conversion to oestrogen) normally stops the long bones from growing after puberty. This increase in height is maintained throughout life.

How many babies are born XXY?

Affected Populations

47, XXY (KS) is the most common human sex chromosome disorder and occurs in approximately 1 in 500-1,000 males. It is estimated that 3,000 affected boys are born each year in the United States.

Can females have XXY syndrome?

A few 47,XXY cases with a female phenotype have been reported. These individuals have positive SRY (testis-determining factor). The genetic explanation of this phenomenon is unclear. Case: A 34-year-old woman presented with testicular feminization and a 47,XXY karyotype.

Does Klinefelter syndrome affect IQ?

Research has shown that the average intelligence (sometimes known as IQ) of boys with Klinefelter Syndrome is lower than that of boys with the usual number of chromosomes. In one study, the average IQ score was 98 for boys with Klinefelter compared with a value of 112 in the other boys.

Does Klinefelter syndrome affect teeth?

Consequently, males affected by KS have larger teeth than males with a normal chromosomal complement (19, 32, 36, 44, 47-49). The importance of the X chromosome to tooth size is directly related to the number of extra X chromosomes, and its effect on general growth patterns and enamel thickness (50).

Are XYY males infertile?

Nonmosaic 47, XYY syndrome is an aneuploidy of sex chromosomes. It is often associated with male infertility. In our study the incidence rate was 0.1% (21/19,842) which is in accordance with a previously reported incidence rate.

Can a girl have an extra Y chromosome?

Most males have XY chromosomes and most women have XX chromosomes. But there are girls and women who have XY chromosomes. This can happen, for example, when a girl has androgen insensitivity syndrome.

Why are XXY males infertile?

Treatment for Infertility

Between 95% and 99% of XXY men are infertile because they do not produce enough sperm to fertilize an egg naturally. But, sperm are found in more than 50% of men with KS. Advances in assistive reproductive technology (ART) have made it possible for some men with KS to conceive.