What are the 3 stages of liver damage in order?

What are the Four Stages of Liver Disease?
  • Causes of Liver Disease. Liver disease refers to any condition that negatively impacts your liver. ...
  • Stages of Liver Disease. ...
  • Stage 1: Inflammation. ...
  • Stage 2: Fibrosis. ...
  • Stage 3: Cirrhosis. ...
  • Stage 4: Liver Failure.

Is Stage 3 liver disease reversible?

During stage 3, fluid accumulates in the abdominal cavity. Clinical symptoms become obvious, including weight loss, yellowing skin, fatigue, and confusion. Cirrhosis has become irreversible. Diagnosed at stage 3, the 1-year survival rate is 80%.

What is stage 2 liver disease?

Stage 2 is liver fibrosis or liver scarring, caused by chronic inflammation. Scarred tissue begins to replace healthy tissue, which reduces how well your liver functions. Liver scar tissue also reduces blood flow to your liver.

What is Stage 3 fatty liver disease?

The third stage of NAFLD is fibrosis;

This occurs when there is persistent scar tissue in the liver and in the blood vessels around the liver. The liver can still function quite well at this stage, and removing or treating the cause of the inflammation may prevent further progression or even reverse some of the damage.

What is the progression of liver disease?

When liver damage progresses to an advanced stage, fluid collects in the legs, called edema, and in the abdomen, called ascites. Ascites can lead to bacterial peritonitis, a serious infection. When the liver slows or stops producing the proteins needed for blood clotting, a person will bruise or bleed easily.

Alcoholic Liver Disease, Animation

How quickly does liver damage progress?

Most often, liver failure happens gradually, over many years. It's the final stage of many liver diseases. But a rarer condition known as acute liver failure happens rapidly (in as little as 48 hours) and can be difficult to detect at first.

How quickly does liver failure happen?

Acute liver failure can happen in as little as 48 hours. It's important to seek medical treatment at the first signs of trouble. These signs may include fatigue, nausea, diarrhea, and discomfort in your right side, just below your ribs.

What is the life expectancy of someone with fatty liver disease?

On average, life expectancy was 2.8 (95% CI = 0.4–5.6) years lower in patients with NAFLD than the general population: 2.4 (95% CI = 0.4–4.5) years for females and 3.1 (95% CI 0.4–6.6) years for males (Table 3).

How long does it take a fatty liver to turn into cirrhosis?

Patients with alcoholic fatty liver disease who continue to consume large amounts of alcohol daily have been found to have a risk of 8–30% of developing fibrosis or cirrhosis after 10 years.

Can a fatty liver cause sudden death?

Is Fatty Liver a Cause of Death? Fatty liver has been reported as a cause of sudden death (54). In a study of alcohol-related deaths from Baltimore examined between 1957 and 1966, fatty liver and cirrhosis were noted to have increased as a cause of death (55).

What are 4 warning signs of a damaged liver?

If signs and symptoms of liver disease do occur, they may include:
  • Skin and eyes that appear yellowish (jaundice)
  • Abdominal pain and swelling.
  • Swelling in the legs and ankles.
  • Itchy skin.
  • Dark urine color.
  • Pale stool color.
  • Chronic fatigue.
  • Nausea or vomiting.

What is the difference between liver damage and liver disease?

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Can Stage 4 liver disease be cured?

Stage 4: Liver Failure

At this stage, the liver cannot be repaired on its own or with treatments; a liver transplant is the only option for recovery. Liver failure can be acute or chronic.

Is Stage 3 liver failure serious?

There are other complications, however, that can arise from Stage 3. It's at this stage that you start to be most susceptible to developing liver cancer. At this point, it's critical to stop further scarring of liver tissue. Left unchecked, you're at risk for an even worse situation.

What are the last stages of liver failure before death?

Changes that can occur with end-stage liver disease include: jaundice; increased risk of bleeding; buildup of fluid in the abdomen; and.
Other symptoms of end-stage liver disease include:
  • muscle cramps;
  • trouble sleeping at night;
  • fatigue ;
  • decreased appetite and intake of food; and.
  • depression .

Can you live 20 years with cirrhosis?

People with cirrhosis in Class A have the best prognosis, with a life expectancy of 15 to 20 years. People with cirrhosis in Class B are still healthy, with a life expectancy of 6 to 10 years. As a result, these people have plenty of time to seek sophisticated therapy alternatives such as a liver transplant.

What's worse fatty liver or cirrhosis?

Fatty liver disease doesn't cause major problems for most people. However, it can turn into a more serious problem if it progresses into cirrhosis of the liver. Untreated cirrhosis of the liver eventually leads to liver failure or liver cancer. Your liver is an organ you can't live without.

What are signs that cirrhosis of the liver is getting worse?

If cirrhosis gets worse, some of the symptoms and complications include: yellowing of the skin and whites of the eyes (jaundice) vomiting blood. itchy skin.

How can you tell the difference between fatty liver and cirrhosis?

Compared with a normal liver (left), a fatty liver (right) appears enlarged and discolored. Tissue samples reveal fat deposits in nonalcoholic fatty liver disease, while inflammation and advanced scarring (cirrhosis) are visible in nonalcoholic steatohepatitis.

What is the most common cause of death in patients with cirrhosis?


Infections are a leading cause of death in patients with cirrhosis and mortality has been reported as high as 19% in one study[76].

How do I know if my fatty liver is getting worse?

If you've been diagnosed with any fatty liver disease, let your health care provider know if you have any symptoms that mean the disease is getting worse. These include fatigue, loss of appetite, weight loss, weakness, fluid retention, or bleeding.

Can you live a full life with fatty liver?

You may live the rest of your natural life without having any complications from it. It becomes more complicated for a small percentage of people when it turns to steatohepatitis (NASH), and especially when NASH progresses to cirrhosis. Research suggests that NAFLD overall may lower life expectancy by four years.

Is liver failure a slow death?

Liver failure can develop slowly or rapidly, depending on the cause and the condition of the liver.

How do you feel when your liver fails?

Acute liver failure can develop quickly in an otherwise healthy person, and it is life-threatening. If you or someone you know suddenly develops a yellowing of the eyes or skin; tenderness in the upper abdomen; or any unusual changes in mental state, personality or behavior, seek medical attention right away.

What happens when the liver starts to shut down?

Liver failure can affect many of your body's organs. Acute liver failure can cause such complications as infection, electrolyte deficiencies and bleeding. Without treatment, both acute and chronic liver failure may eventually result in death.